The induction of tumour suppressor protein P53 limits the entry of cells into the pluripotent inner cell mass lineage in the mouse embryo
Author:
Funder
Australian NHMRC
Publisher
Elsevier BV
Subject
Cell Biology
Reference52 articles.
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2. p53 in health and disease;Vousden;Nat. Rev. – Mol. Cell Biol.,2007
3. Transformation-related protein 53 expression in the early mouse embryo compromises preimplantation embryonic development by preventing the formation of a proliferating inner cell mass;Ganeshan;Biol. Reprod.,2010
4. Preimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway;Jin;Biol. Reprod.,2009
5. Culture of zygotes increases TRP53 expression in b6 mouse embryos which reduces embryo viability;Li;Biol. Reprod.,2007
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