Replication-dependent irreversible topoisomerase 1 poisoning is responsible for FdUMP[10] anti-leukemic activity
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Cell Biology,Genetics,Hematology,Molecular Biology
Reference35 articles.
1. Novel approaches to the treatment of acute myeloid leukemia;Roboz;Hematology Am Soc Hematol Educ Program,2011
2. Genetic abnormalities and challenges in the treatment of acute myeloid leukemia;Kumar;Genes Cancer,2011
3. Treatment of older patients with AML;Buchner;Crit Rev Oncol Hematol,2005
4. Current and emerging therapies for acute myeloid leukemia;Robak;Clin Ther,2009
5. Unique dual targeting of thymidylate synthase and topoisomerase 1 by FdUMP[10] results in high efficacy against AML and low toxicity;Pardee;Blood,2012
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