Advances in detecting and reducing off-target effects generated by CRISPR-mediated genome editing
Author:
Funder
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
Genetics,Molecular Biology
Reference90 articles.
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2. A highly specific SpCas9 variant is identified by in vivo screening in yeast;Casini;Nat. Biotechnol.,2018
3. Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage;Cencic;PLoS One,2014
4. Enhanced proofreading governs CRISPR-Cas9 targeting accuracy;Chen;Nature,2017
5. Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases;Cho;Genome Res.,2014
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