mTOR and cancer: many loops in one pathway
Author:
Publisher
Elsevier BV
Subject
Cell Biology
Reference58 articles.
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2. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery;Kim;Cell,2002
3. GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR;Kim;Mol Cell,2003
4. Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control;Loewith;Mol Cell,2002
5. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival;Peterson;Cell,2009
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