Recent Advances in the Discovery and Development of CRTh2 Antagonists
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Publisher
Elsevier
Reference50 articles.
1. PGD2 Antagonists
2. Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases
3. Differential modulation of human basophil functions through prostaglandin D2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2
Cited by 15 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. The synthesis of 2,3,6-trisubstituted 1-oxo-1,2-dihydroisoquinolines as potent CRTh 2 antagonists;Bioorganic & Medicinal Chemistry Letters;2017-12
2. Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of sulphone-based CRTh2 antagonists;European Journal of Medicinal Chemistry;2016-05
3. Synthesis of a high specific activity methyl sulfone tritium isotopologue of fevipiprant (NVP-QAW039);Journal of Labelled Compounds and Radiopharmaceuticals;2015-04-16
4. Structure–activity relationships (SAR) and structure–kinetic relationships (SKR) of bicyclic heteroaromatic acetic acids as potent CRTh2 antagonists III: The role of a hydrogen-bond acceptor in long receptor residence times;Bioorganic & Medicinal Chemistry Letters;2014-11
5. Structure–activity relationships (SAR) and structure–kinetic relationships (SKR) of bicyclic heteroaromatic acetic acids as potent CRTh2 antagonists II: Lead optimization;Bioorganic & Medicinal Chemistry Letters;2014-11
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