Pharmacological variability of insulins degludec and glargine 300 U/mL: Equivalent or not?

Author:

Monnier L.,Colette C.

Publisher

Elsevier BV

Subject

Endocrinology,General Medicine,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference15 articles.

1. Morning administration of 0.4U/kg/day insulin glargine 300U/mL provides less fluctuating 24-hour pharmacodynamics and more even pharmacokinetic profiles compared with insulin degludec 100U/mL in type 1 diabetes;Bailey;Diabetes Metab,2017

2. New insulin glargine 300units.mL−1 provides a more even activity profile and prolonged glycemic control at steady state compared with insulin glargine 100units.mL−1;Becker;Diabetes Care,2015

3. A review of the pharmacological properties of insulin degludec and their clinical relevance;Haahr;Clin Pharmacokinet,2014

4. Basal insulin analogues in the management of diabetes mellitus: what progress have we made?;Owens;Diabetes Metab Res Rev,2014

5. Pharmacokinetics and pharmacodynamics of biosimilar insulins: is clamp technology fit for purpose?;Home;Diabetes Care,2015

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