Structural mechanism underlying ligand binding and activation of PPARγ-Reference-Cited by-同舟云学术

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Structural mechanism underlying ligand binding and activation of PPARγ

Published:2021-09 Issue:9 Volume:29 Page:940-950.e4
ISSN:0969-2126
Container-title:Structure
language:en
Short-container-title:Structure

Author:

Shang Jinsai^ORCID,Kojetin Douglas J.^ORCID

Funder

National Institute of General Medical Sciences

National Institute of Diabetes and Digestive and Kidney Diseases

National Institutes of Health

Office of Science

Basic Energy Sciences

Biological and Environmental Research

U.S. Department of Energy

SLAC National Accelerator Laboratory

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference68 articles.

1. Ligand entry pathways in the ligand binding domain of PPARγ receptor;Aci-Sèche;FEBS Lett.,2011

2. The Phenix software for automated determination of macromolecular structures;Adams;Methods,2011

3. Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor β/δ (FABP5-PPARβ/δ) signaling pathway;Armstrong;J. Biol. Chem.,2014

4. Mechanistic elucidation guided by covalent inhibitors for the development of anti-diabetic PPARγ ligands;Bae;Chem. Sci.,2016

5. Conformational diversity of the helix 12 of the ligand binding domain of PPARγ and functional implications;Batista;J. Phys. Chem. B,2015

Cited by 25 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Structure-based screening, optimization and biological evaluation of novel chrysin-based derivatives as selective PPARγ modulators for the treatment of T2DM and hepatic steatosis;European Journal of Medicinal Chemistry;2024-10

2. Cladosporols and PPARγ: Same Gun, Same Bullet, More Targets;Biomolecules;2024-08-13

3. Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARγ;2024-07-18

4. Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARγ;2024-07-18

5. Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARgamma;2024-05-15

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