Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding-Reference-Cited by-同舟云学术

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Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding

Published:2019-05 Issue:5 Volume:27 Page:837-845.e3
ISSN:0969-2126
Container-title:Structure
language:en
Short-container-title:Structure

Author:

Hou Peini,Huang Chang,Liu Chao-Pei,Yang Na,Yu Tianshu,Yin Yuxin,Zhu Bing,Xu Rui-Ming

Funder

Ministry of Science and Technology of China

Natural Science Foundation of China

Strategic Priority Research Program

Chinese Academy of Sciences

Peking University

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference27 articles.

1. PHENIX: a comprehensive Python-based system for macromolecular structure solution;Adams;Acta Crystallogr. D Biol. Crystallogr.,2010

2. Crystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanism;An;J. Biol. Chem.,2011

3. Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain;Bowman;Structure,2006

4. The trithorax group proteins Kismet and ASH1 promote H3K36 dimethylation to counteract Polycomb group repression in Drosophila;Dorighi;Development,2013

5. Coot: model-building tools for molecular graphics;Emsley;Acta Crystallogr. D Biol. Crystallogr.,2004

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1. PHD-BAH Domain in ASH1L Could Recognize H3K4 Methylation and Regulate the Malignant Behavior of Cholangiocarcinoma;Anti-Cancer Agents in Medicinal Chemistry;2024-10

2. Expansion of the Genotypic and Phenotypic Spectrum of ASH1L-Related Syndromic Neurodevelopmental Disorder;Genes;2024-03-28

3. Exploring host epigenetic enzymes as targeted therapies for visceral leishmaniasis: in silico design and in vitro efficacy of KDM6B and ASH1L inhibitors;Molecular Diversity;2024-03-24

4. Widespread alteration of protein autoinhibition in human cancers;Cell Systems;2024-03

5. Structural and functional insights into the epigenetic regulator MRG15;Acta Pharmacologica Sinica;2024-01-08

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