Machine learning prediction of methionine and tryptophan photooxidation susceptibility
Author:
Funder
AstraZeneca
Publisher
Elsevier BV
Subject
Genetics,Molecular Biology,Molecular Medicine
Reference89 articles.
1. Isomerization and oxidation in the complementarity-determining regions of a monoclonal antibody: A study of the modification-structure-function correlations by hydrogen-deuterium exchange mass spectrometry;Yan;Anal. Chem.,2016
2. Chemical instability of protein pharmaceuticals: Mechanisms of oxidation and strategies for stabilization;Li;Biotechnol. Bioeng.,1995
3. Rapid assessment of oxidation via middle-down LCMS correlates with methionine side-chain solvent-accessible surface area for 121 clinical stage monoclonal antibodies;Yang;MAbs,2017
4. Sulphur atoms from methionines interacting with aromatic residues are less prone to oxidation;Aledo;Sci. Rep.,2015
5. Molecular dynamics simulations and oxidation rates of methionine residues of granulocyte colony-stimulating factor at different pH values;Chu;Biochemistry,2004
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