Synthesis and anti-inflammatory activity of 5-(6-methyl-2-substituted 4-pyrimidinyloxymethyl)-1,3,4-oxadiazole-2-thiones and their 3-morpholinomethyl derivatives

Author:

Jakubkien≐ Virginija,Burbulien≐ Milda Malvina,Mekuškien≐ Giedrut≐,Udr≐nait≐ Emilija,Gaidelis Povilas,Vainilavičius Povilas

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmaceutical Science

Reference19 articles.

1. 1,3,4-Oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole analogs of the fenamates in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities;Boschelli;J. Med. Chem.,1993

2. Synthesis of formazans of substituted oxadiazole-2(3H)-thiones;Kalsi;Indian J. Chem.,1988

3. Synthesis and anti-inflammatory activity of oxadiazoline thione hydrochlorides;Singh;Eur. J. Med. Chem.—Chim. Ther.,1986

4. Synthesis and pharmacological screening of some new 2-thioxo-3-(substituted aminomethyl)-5-(3,5-dinitrophenyl)-1,3,4-oxadiazoles;Nigam;J. Indian Chem. Soc.,1992

5. 1,3,4-Oxadiazolethiones as inflammation inhibitors;Saxena;Indian J. Pharm. Sci.,1992

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