Structure–activity relationships (SAR) and structure–kinetic relationships (SKR) of bicyclic heteroaromatic acetic acids as potent CRTh2 antagonists III: The role of a hydrogen-bond acceptor in long receptor residence times-Reference-Cited by-同舟云学术

Structure–activity relationships (SAR) and structure–kinetic relationships (SKR) of bicyclic heteroaromatic acetic acids as potent CRTh2 antagonists III: The role of a hydrogen-bond acceptor in long receptor residence times

Published:2014-11 Issue:21 Volume:24 Page:5127-5133
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Alonso Juan Antonio,Andrés Miriam,Bravo Mónica,Buil Maria Antonia,Calbet Marta,Castro Jordi,Eastwood Paul R.,Esteve Cristina,Ferrer Manel,Forns Pilar,Gómez Elena,González Jacob,Lozoya Estrella,Mir Marta,Moreno Imma,Petit Silvia,Roberts Richard S.,Sevilla Sara,Vidal Bernat,Vidal Laura,Vilaseca Pere

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference45 articles.

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2. The roles of the prostaglandin D2 receptors DP1 and CRTH2 in promoting allergic responses

3. Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2

4. Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells Activation in Vivo Increases Blood Leukocyte Counts and Its Blockade Abrogates 13,14-Dihydro-15-keto-prostaglandin D2-Induced Eosinophilia in Rats

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