The ester derivatives obtained by C-ring modification of podophyllotoxin induce apoptosis and inhibited proliferation in PC-3M cells via down-regulation of PI3K/Akt signaling pathway-Reference-Cited by-同舟云学术

The ester derivatives obtained by C-ring modification of podophyllotoxin induce apoptosis and inhibited proliferation in PC-3M cells via down-regulation of PI3K/Akt signaling pathway

Published:2021-08 Issue: Volume:46 Page:128174
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Zhao Yan,Li Danyao,Wei Minggang,Du Rui,Yan Zhaowei

Funder

Jiangsu Provincial Medical Youth Talent

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. Desmoid tumors: are they benign or malignant;Alman,2012

2. Three different ultrasound diagnostic methods in differential diagnosis of benign and malignant breast masses;Yuan;J Med Imag,2010

3. Isolation of podophyllotoxin from Callitrus drummondii;Kier;J Pharm Sci,2010

4. Discovery of podophyllotoxins;Imbert;Biochimie,1998

5. 4β-[4′-(1-(Aryl)ureido)benzamide]podophyllotoxins as DNA topoisomerase I and IIα inhibitors and apoptosis inducing agents;Kamal;Bioorg Med Chem,2013

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