Alkyl-bridged substituted 8-arylquinolines as highly potent PDE IV inhibitors-Reference-Cited by-同舟云学术

Alkyl-bridged substituted 8-arylquinolines as highly potent PDE IV inhibitors

Published:2009-09 Issue:17 Volume:19 Page:5266-5269
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Lacombe Patrick,Chauret Nathalie,Claveau David,Day Stephen,Deschênes Denis,Dubé Daniel,Gallant Michel,Girard Yves,Huang Zheng,Laliberté France,Lévesque Jean-Francois,Liu Susana,Macdonald Dwight,Mancini Joseph A.,Masson Paul,Nicholson Donald W.,Nicoll-Griffith Deborah A.,Salem Myriam,Styhler Angela,Young Robert N.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference31 articles.

1. Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents

2. Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use

3. Genomic organization of the human phosphodiesterasePDE11Agene

4. Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions

5. Preferential Inhibition of T Helper 1, but Not T Helper 2, Cytokines in Vitro by L-826,141 [4-{2-(3,4-Bisdifluromethoxyphenyl)-2-{4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl}-3-methylpyridine-1-oxide], a Potent and Selective Phosphodiesterase 4 Inhibitor

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