Divergent synthesis of kinase inhibitor derivatives, leading to discovery of selective Gck inhibitors
Author:
Funder
MEXT
AMED
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry
Reference18 articles.
1. Synthesis and evaluation of 5-substituted 9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as check point 1 kinase inhibitors
2. Synthesis of C-Glycosyl Pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as a Scaffold for Check Point Kinase 1 Inhibitors
3. The Orally Available Spleen Tyrosine Kinase Inhibitor 2-[7-(3,4-Dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino]nicotinamide Dihydrochloride (BAY 61-3606) Blocks Antigen-Induced Airway Inflammation in Rodents
4. A novel retinoblastoma therapy from genomic and epigenetic analyses
5. Therapeutic Potential of Spleen Tyrosine Kinase Inhibition for Treating High-Risk Precursor B Cell Acute Lymphoblastic Leukemia
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