Imidazo[1,5-a]pyrazines: Orally efficacious inhibitors of mTORC1 and mTORC2-Reference-Cited by-同舟云学术

Imidazo[1,5-a]pyrazines: Orally efficacious inhibitors of mTORC1 and mTORC2

Published:2011-04 Issue:7 Volume:21 Page:2092-2097
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Crew Andrew P.,Bhagwat Shripad V.,Dong Hanqing,Bittner Mark A.,Chan Anna,Chen Xin,Coate Heather,Cooke Andrew,Gokhale Prafulla C.,Honda Ayako,Jin Meizhong,Kahler Jennifer,Mantis Christine,Mulvihill Mark J.,Tavares-Greco Paula A.,Volk Brian,Wang Jing,Werner Douglas S.,Arnold Lee D.,Pachter Jonathan A.,Wild Robert,Gibson Neil W.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference28 articles.

1. Current development of mTOR inhibitors as anticancer agents

2. Defining the Role of mTOR in Cancer

3. TOR Signaling in Growth and Metabolism

4. Targeting the mTOR signaling network in cancer

5. Targeting the mTOR Signaling Network for Cancer Therapy

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