Hit-to-Lead studies: The discovery of potent, orally bioavailable thiazolopyrimidine CXCR2 receptor antagonists-Reference-Cited by-同舟云学术

Hit-to-Lead studies: The discovery of potent, orally bioavailable thiazolopyrimidine CXCR2 receptor antagonists

Published:2006-02 Issue:4 Volume:16 Page:960-963
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Baxter Andrew,Cooper Anne,Kinchin Elizabeth,Moakes Kerry,Unitt John,Wallace Alan

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference7 articles.

1. The Design of Leadlike Combinatorial Libraries

2. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

3. Hit-to-Lead studies: The discovery of potent, orally bioavailable triazolethiol CXCR2 receptor antagonists

4. For full details of the biological assays used see: Austen, R.; Baxter, A.; Bonnert, R.; Hunt, F.; Kinchin, E.; Willis, P. Int. Patent Appl. WO 00/09511.

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