Addition of hydrophobic side chains improve the apoptosis inducibility of the human glyoxalase I inhibitor, TLSC702-Reference-Cited by-同舟云学术

Addition of hydrophobic side chains improve the apoptosis inducibility of the human glyoxalase I inhibitor, TLSC702

Published:2021-05 Issue: Volume:40 Page:127918
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Azuma Miku,Inoue Manami,Nishida Aya,Akahane Haruka,Kitajima Masataka,Natani Shunsuke,Chimori Ryusei,Yoshimori Atsushi,Mano Yasunari,Uchiro Hiromi,Tanuma Sei-ichi,Takasawa Ryoko

Funder

Japan Society for the Promotion of Science

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference28 articles.

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2. Effect of methylglyoxal on human leukaemia 60 cell growth: Modification of DNA, G1 growth arrest and induction of apoptosis;Kang;Leuk Res,1996

3. Analysis of glyoxalase-I from normal and tumor tissue;Ranganathan;Biochim Biophys Acta,1993

4. Glyoxalase I (GLO1) is up-regulated in pancreatic cancerous tissues compared with related non-cancerous tissues;Wang;Anticancer Res,2012

5. Glyoxalase-I is a novel prognosis factor associated with gastric cancer progression;Cheng;PLoS ONE,2012

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3. Crystal structures of human glyoxalase I and its complex with TLSC702 reveal inhibitor binding mode and substrate preference;FEBS Letters;2022-04-08

4. Triphenylbismuth dichloride inhibits human glyoxalase I and induces cytotoxicity in cultured cancer cell lines;The Journal of Toxicological Sciences;2022