Phthalazinones. Part 1: The design and synthesis of a novel series of potent inhibitors of poly(ADP-ribose)polymerase-Reference-Cited by-同舟云学术

Phthalazinones. Part 1: The design and synthesis of a novel series of potent inhibitors of poly(ADP-ribose)polymerase

Published:2005-05 Issue:9 Volume:15 Page:2235-2238
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Loh Vincent M.,Cockcroft Xiao-ling,Dillon Krystyna J.,Dixon Lesley,Drzewiecki Jan,Eversley Penny J.,Gomez Sylvie,Hoare Janet,Kerrigan Frank,Matthews Ian T.W.,Menear Keith A.,Martin Niall M.B.,Newton Roger F.,Paul Jane,Smith Graeme C.M.,Vile Julia,Whittle Alan J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference15 articles.

1. Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

2. Poly(ADP-ribose) synthetase, a main acceptor of poly(ADP-ribose) in isolated nuclei.

3. Role of poly(ADP-ribose) formation in DNA repair

4. 4-Amino-1,8-naphthalimide: a novel inhibitor of poly(ADP-ribose) polymerase and radiation sensitizer

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