Conformationally restricted homotryptamines. Part 5: 3-(trans-2-aminomethylcyclopentyl)indoles as potent selective serotonin reuptake inhibitors-Reference-Cited by-同舟云学术

Conformationally restricted homotryptamines. Part 5: 3-(trans-2-aminomethylcyclopentyl)indoles as potent selective serotonin reuptake inhibitors

Published:2009-08 Issue:15 Volume:19 Page:4031-4033
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Denhart Derek J.,Deskus Jeffrey A.,Ditta Jonathan L.,Gao Qi,Dalton King H.,Kozlowski Edward S.,Meng Zhaoxing,LaPaglia Melissa A.,Mattson Gail K.,Molski Thaddeus F.,Taber Matthew T.,Lodge Nicholas J.,Mattson Ronald J.,Macor John E.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference15 articles.

1. Serotonin Reuptake Inhibition: An Update on Current Research Strategies

2. Treatment-Resistant Depression

3. Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 4

4. Design, synthesis and biological evaluation of new 3-[(4-aryl)piperazin-1-yl]-1-arylpropane derivatives as potential antidepressants with a dual mode of action: serotonin reuptake inhibition and 5-HT1A receptor antagonism

5. Studies towards the next generation of antidepressants. Part 4: Derivatives of 4-(5-fluoro-1H-indol-3-yl)cyclohexylamine with affinity for the serotonin transporter and the 5-HT1A receptor

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