In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor-Reference-Cited by-同舟云学术

In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor

Published:2018-11 Issue:20 Volume:28 Page:3404-3408
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Vaupel Andrea,Holzer Philipp,Ferretti Stephane,Guagnano Vito,Kallen Joerg^ORCID,Mah Robert,Masuya Keiichi,Ruetz Stephan,Rynn Caroline^ORCID,Schlapbach Achim^ORCID,Stachyra Thérèse,Stutz Stefan,Todorov Milen,Jeay Sébastien,Furet Pascal

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference21 articles.

1. For recent reviews on the topic see:;Burgess;Front Oncol,2016

2. Recent Advances of p53-MDM2 Small Molecule Inhibitors (2011-Present)

3. Drugging the p53 pathway: understanding the route to clinical efficacy

4. Targeting MDM2-p53 Interaction for Cancer Therapy: Are We There Yet?

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