X-ray structure based evaluation of analogs of citalopram: Compounds with increased affinity and selectivity compared with R-citalopram for the allosteric site (S2) on hSERT-Reference-Cited by-同舟云学术

X-ray structure based evaluation of analogs of citalopram: Compounds with increased affinity and selectivity compared with R-citalopram for the allosteric site (S2) on hSERT

Published:2017-02 Issue:3 Volume:27 Page:470-478
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Topiol Sid,Bang-Andersen Benny,Sanchez Connie,Plenge Per,Loland Claus J.,Juhl Karsten,Larsen Krestian,Bregnedal Peter,Bøgesø Klaus P.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference38 articles.

1. Monoaminergic Neurotransmission: The History of the Discovery of Antidepressants from 1950s Until Today

2. Effect of antidepressant drugs on the depletion of intraneuronal brain 5-hydroxytryptamine stores caused by 4-methyl-α-ethyl-meta-tyramine

3. The discovery of citalopram and its refinement to escitalopram;Bøgesø,2013

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Computational Chemistry in Structure-Based Solute Carrier Transporter Drug Design: Recent Advances and Future Perspectives;Journal of Chemical Information and Modeling;2024-01-31

2. Mixed ligand approach for novel hydrazide copper(II) complexes: Structural aspects, theoretical investigation and their biological evaluation;Applied Organometallic Chemistry;2023-05-05

3. Molecular Mechanism for the Allosteric Inhibition of the Human Serotonin Transporter by Antidepressant Escitalopram;ACS Chemical Neuroscience;2022-01-18

4. Antidepressants: Molecular Aspects of SSRIs;NeuroPsychopharmacotherapy;2022

5. Recent Advances and Challenges of the Drugs Acting on Monoamine Transporters;Current Medicinal Chemistry;2020-07-01