Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: Metabolism-directed optimization studies towards orally bioavailable derivatives-Reference-Cited by-同舟云学术

Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: Metabolism-directed optimization studies towards orally bioavailable derivatives

Published:2004-09 Issue:18 Volume:14 Page:4615-4621
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Vergne Fabrice,Bernardelli Patrick,Lorthiois Edwige,Pham Nga,Proust Emmanuelle,Oliveira Chrystelle,Mafroud Abdel-Kader,Ducrot Pierre,Wrigglesworth Roger,Berlioz-Seux Françoise,Coleon Francis,Chevalier Eric,Moreau François,Idrissi Moulay,Tertre Anita,Descours Arnaud,Berna Patrick,Li Mei

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference27 articles.

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