An amide-based sulfenamide prodrug of gamma secretase inhibitor BMS–708163 delivers parent drug from an oral conventional solid dosage form in male beagle dog-Reference-Cited by-同舟云学术

An amide-based sulfenamide prodrug of gamma secretase inhibitor BMS–708163 delivers parent drug from an oral conventional solid dosage form in male beagle dog

Published:2020-02 Issue:3 Volume:30 Page:126856
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Guarino Victor R.,Olson Richard E.,Everlof J. Gerry,Wang Nenghui,McDonald Ivar,Haskell Roy,Clarke Wendy,Lentz Kimberley A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference12 articles.

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2. Guarino, V. R.; Stella, V. J. In Prodrugs: Challenges and Rewards; Stella, V. J., Borchardt, R. T., Hageman, M. J., Oliyai, R., Maag, H, Tilley, J. W. Eds.; Springer: New York, 2007; Part 2, pp 133-187.

3. Prodrugs: Challenges and Rewards; Stella, V. J., Borchardt, R. T., Hageman, M. J., Oliyai, R., Maag, H, Tilley, J. W. Eds.; Springer: New York, 2007; Part 1 & 2.

4. Sulfenamides as prodrugs of NH-acidic compounds: A new prodrug option for the amide bond

5. Guarino VR. Ph.D. Dissertation; University of Kansas, 2004.

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