Discovery of potent, selective and orally bioavailable imidazo[1,5-a]pyrazine derived ACK1 inhibitors-Reference-Cited by-同舟云学术

Discovery of potent, selective and orally bioavailable imidazo[1,5-a]pyrazine derived ACK1 inhibitors

Published:2013-02 Issue:4 Volume:23 Page:979-984
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Jin Meizhong,Wang Jing,Kleinberg Andrew,Kadalbajoo Mridula,Siu Kam W.,Cooke Andrew,Bittner Mark A.,Yao Yan,Thelemann April,Ji Qunsheng,Bhagwat Shripad,Mulvihill Kristen M.,Rechka Josef A.,Pachter Jonathan A.,Crew Andrew P.,Epstein David,Mulvihill Mark J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

2. Prieto-Echague, V.; Miller, W. T. J. Signal Transduct. 2011, article ID 742372.

3. Shepherding AKT and androgen receptor by Ack1 tyrosine kinase

4. Somatic mutation in the ACK1 ubiquitin association domain enhances oncogenic signaling through EGFR regulation in renal cancer derived cells

5. Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

Cited by 18 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, Synthesis, and Evaluation of (R)-8-((Tetrahydrofuran-2-yl)methyl)pyrido[2,3-d]pyrimidin-7-ones as Novel Selective ACK1 Inhibitors to Combat Acquired Resistance to the Third-Generation EGFR Inhibitor;Journal of Medicinal Chemistry;2023-05-03

2. Domain Architecture of the Nonreceptor Tyrosine Kinase Ack1;Cells;2023-03-15

3. Identification of Activated Cdc42-Associated Kinase Inhibitors as Potential Anticancer Agents Using Pharmacoinformatic Approaches;Biomolecules;2023-01-22

4. Small Molecules Targeting Activated Cdc42-Associated Kinase 1 (ACK1/TNK2) for the Treatment of Cancers;Journal of Medicinal Chemistry;2021-11-04

5. Iodine‐Catalyzed Double [4+2] Oxidative Annulations for the Synthesis of Bipyrazines from Ketones and Diamines by a Domino Strategy;Advanced Synthesis & Catalysis;2021-10-13