Synthesis and SAR of substituted pyrazolo[1,5-a]quinazolines as dual mGlu2/mGlu3 NAMs-Reference-Cited by-同舟云学术

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Synthesis and SAR of substituted pyrazolo[1,5-a]quinazolines as dual mGlu2/mGlu3 NAMs

Published:2014-06 Issue:12 Volume:24 Page:2693-2698
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Wenthur Cody J.,Morrison Ryan D.,Daniels J. Scott,Conn P. Jeffrey,Lindsley Craig W.

Funder

NIH/MLPCN

Vanderbilt Specialized Chemistry Center for Accelerated Probe Development

William K. Warren, Jr. Chair in Medicine

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference28 articles.

1. PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS

2. Allosteric Modulation of Seven Transmembrane Spanning Receptors: Theory, Practice, and Opportunities for Central Nervous System Drug Discovery

3. Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

4. Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

5. Review: The group II metabotropic glutamate receptor 3 (mGluR3, mGlu3, GRM3): expression, function and involvement in schizophrenia

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1. Discovery of 6,7-Dihydropyrazolo[1,5-a]pyrazin-4(5H)-one Derivatives as mGluR₂ Negative Allosteric Modulators with In Vivo Activity in a Rodent’s Model of Cognition;Journal of Medicinal Chemistry;2024-08-29

2. Biological activities of recent advances in quinazoline;Recent Advances on Quinazoline;2024-02-21

3. Design, Synthesis, Antitumour Evaluation, and In Silico Studies of Pyrazolo-[1,5-c]quinazolinone Derivatives Targeting Potential Cyclin-Dependent Kinases;Molecules;2023-09-13

4. Synthesis of pyrimido[1,2-a]indoles (minireview);Chemistry of Heterocyclic Compounds;2021-10

5. International Union of Basic and Clinical Pharmacology. CXI. Pharmacology, Signaling, and Physiology of Metabotropic Glutamate Receptors;Pharmacological Reviews;2020-12-23

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