A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor-Reference-Cited by-同舟云学术

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A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor

Published:2011-05 Issue:10 Volume:21 Page:2877-2881
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Bach Peter,Boström Jonas,Brickmann Kay,van Giezen J.J.J.,Hovland Ragnar,Petersson Annika U.,Ray Asim,Zetterberg Fredrik

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. Advances in antiplatelet therapy: overview of new P2Y12 receptor antagonists in development

2. Biology and Pharmacology of the Platelet P2Y12 Receptor

3. Effects of Clopidogrel in Addition to Aspirin in Patients with Acute Coronary Syndromes without ST-Segment Elevation

4. Identification and Biological Activity of the Active Metabolite of Clopidogrel

5. The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel?s active metabolite

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The proof of concept of 2-{3-[N-(1-benzylpiperidin-4-yl)propyl]amino}-6-[N-methyl-N-(prop-2-yn-1-yl)amino]-4-phenylpyridine-3,5-dicarbonitrile for the therapy of neuropathic pain;Bioorganic Chemistry;2024-09

2. Strategies for targeting the P2Y12 receptor in the central nervous system;Bioorganic & Medicinal Chemistry Letters;2022-09

3. P2Y12 antagonists: Approved drugs, potential naturally isolated and synthesised compounds, and related in-silico studies;European Journal of Medicinal Chemistry;2022-01

4. Novel Thienopyrimidine-Based PET Tracers for P2Y12 Receptor Imaging in the Brain;ACS Chemical Neuroscience;2021-11-10

5. Synthesis, insecticidal activities, and structure–activity relationships of 1,3,4‐oxadiazole‐ring‐containing pyridylpyrazole‐4‐carboxamides as novel insecticides of the anthranilic diamide family;Journal of Heterocyclic Chemistry;2021-07-27

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