Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors-Reference-Cited by-同舟云学术

Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors

Published:2012-01 Issue:2 Volume:22 Page:1136-1141
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Suda Atsushi,Koyano Hiroshi,Hayase Tadakatsu,Hada Kihito,Kawasaki Ken-ichi,Komiyama Susumu,Hasegawa Kiyoshi,Fukami Takaaki A.,Sato Shigeo,Miura Takaaki,Ono Naomi,Yamazaki Toshikazu,Saitoh Ryoichi,Shimma Nobuo,Shiratori Yasuhiko,Tsukuda Takuo

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference23 articles.

1. Hsp90: Chaperoning signal transduction

2. HSP90 as a new therapeutic target for cancer therapy: the story unfolds

3. HSP90: a rising star on the horizon of anticancer targets

4. Heat shock protein 90: The cancer chaperone

5. Crystal Structure of an Hsp90–Geldanamycin Complex: Targeting of a Protein Chaperone by an Antitumor Agent

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