Synthesis of N,N′-disubstituted 3-aminobenzo[c] and [d]azepin-2-ones as potent and specific farnesyl transferase inhibitors-Reference-Cited by-同舟云学术

Synthesis of N,N′-disubstituted 3-aminobenzo[c] and [d]azepin-2-ones as potent and specific farnesyl transferase inhibitors

Published:2004-02 Issue:3 Volume:14 Page:767-771
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Le Diguarher Thierry,Ortuno Jean-Claude,Shanks David,Guilbaud Nicolas,Pierré Alain,Raimbaud Eric,Fauchère Jean-Luc,Hickman John A,Tucker Gordon C,Casara Patrick J

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference17 articles.

1. Evidence for a Catalytic Role of Zinc in Protein Farnesyltransferase

2. Farnesyltransferase inhibitors: mechanism and applications

3. Farnesyltransferase inhibitors: promises and realities

4. Farnesyl transferase inhibitors as anticancer agents

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