The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screening-Reference-Cited by-同舟云学术

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The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screening

Published:2024-04 Issue: Volume:102 Page:129675
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Hartman George^ORCID,Humphries Paul,Hughes Robert,Ho Andrew,Montgomery Rusty,Deshpande Aditi,Mahanta Maitriyee,Tronnes Sarah^ORCID,Cowdin Samantha,He Xu,Liu Fangchao,Zhang Lifang,Liu Chuan,Dou Dengfeng,Li Jin,Spasic Aleksander,Coll Rebecca^ORCID,Marleaux Michael,Hochheiser Inga V.,Geyer Matthias^ORCID,Rubin Paul,Fortney Kristen,Wilhelmsen Kevin

Publisher

Elsevier BV

Reference30 articles.

1. NLRP3 and pyroptosis blockers for treating inflammatory diseases;Coll;Trends Pharmacol Sci,2022

2. Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3;Hochheiser;Nature,2022

3. ATP-binding and hydrolysis of human NLRP3;Brinkschulte;Commun Biol,2022

4. NLRP3 inflammasome priming: a riddle wrapped in a mystery inside an enigma;McKee;J Leukoc Bio,2020

5. Cryo-EM structures of the active NLRP3 inflammasome disc;Xiao;Nature,2023

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Re-Evaluating PIN1 as a Therapeutic Target in Oncology Using Neutral Inhibitors and PROTACs;Journal of Medicinal Chemistry;2024-09-04

2. Discovery of two non-UDP-mimic inhibitors of O-GlcNAc transferase by screening a DNA-encoded library;Bioorganic Chemistry;2024-06

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