Design, synthesis, and preliminary biological evaluation of novel ethyl 1-(2′-hydroxy-3′-aroxypropyl)-3-aryl-1H-pyrazole-5-carboxylate-Reference-Cited by-同舟云学术

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Design, synthesis, and preliminary biological evaluation of novel ethyl 1-(2′-hydroxy-3′-aroxypropyl)-3-aryl-1H-pyrazole-5-carboxylate

Published:2006-12 Issue:24 Volume:16 Page:6342-6347
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Wei Fang,Zhao Bao-Xiang,Huang Bin,Zhang Lu,Sun Chun-Hui,Dong Wen-Liang,Shin Dong-Soo,Miao Jun-Ying

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference29 articles.

1. Preliminary evaluation in vitro of the inhibition of cell proliferation, cytotoxicity and induction of apoptosis by 1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene

2. Safrole oxide induces apoptosis by activating caspase-3, -8, and -9 in A549 human lung cancer cells

3. Upregulating of Fas, integrin β4 and P53 and depressing of PC-PLC activity and ROS level in VEC apoptosis by safrole oxide

4. Safrole oxide inhibits angiogenesis by inducing apoptosis

5. Discovery of a novel small molecule, 1-ethoxy-3-(3,4-methylenedioxyphenyl)-2-propanol, that induces apoptosis in A549 human lung cancer cells

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