PKI-179: An orally efficacious dual phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor-Reference-Cited by-同舟云学术

PKI-179: An orally efficacious dual phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor

Published:2010-10 Issue:19 Volume:20 Page:5869-5873
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Venkatesan Aranapakam M.,Chen Zecheng,Santos Osvaldo Dos,Dehnhardt Christoph,Santos Efren Delos,Ayral-Kaloustian Semiramis,Mallon Robert,Hollander Irwin,Feldberg Larry,Lucas Judy,Yu Ker,Chaudhary Inder,Mansour Tarek S.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference24 articles.

1. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

2. Ras, PI(3)K and mTOR signalling controls tumour cell growth

3. Regulation of phosphoinositide 3-kinase expression in health and disease

4. Synthesis and Function of 3-Phosphorylated Inositol Lipids

5. PI3K pathway alterations in cancer: variations on a theme

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