Azetidine-based selective glycine transporter-1 (GlyT1) inhibitors with memory enhancing properties
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Published:2020-07
Issue:14
Volume:30
Page:127214
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ISSN:0960-894X
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Container-title:Bioorganic & Medicinal Chemistry Letters
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language:en
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Short-container-title:Bioorganic & Medicinal Chemistry Letters
Author:
Hudson Andrew R., Santora Vincent J., Petroski Robert E., Almos Theresa A., Anderson Gary, Barido Richard, Basinger Jillian, Bellows Chris L., Bookser Brett C., Broadbent Nicola J., Cabebe Clifford, Chai Chih-Kun, Chen Mi, Chow Stephine, Chung De Michael, Heger Lindsay, Danks Anne M., Freestone Graeme C., Gitnick Dany, Gupta Varsha, Hoffmaster Christine, Kaplan Alan P.ORCID, Kennedy Michael R., Lee Dong, Limberis James, Ly Kiev, Mak Chi Ching, Masatsugu Brittany, Morse Andrew C., Na Jim, Neul David, Nikpur John, Renick Joel, Sebring Kristen, Sevidal Samantha, Tabatabaei Ali, Wen Jenny, Xia Shouzhen, Yan Yingzhuo, Yoder Zachary W., Zook Douglas, Peters Marco, Breitenbucher J. Guy
Funder
Dart NeuroScience, LLC
Subject
Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry
Reference24 articles.
1. Glycine transporters: essential regulators of neurotransmission;Eulenburg;Trends Biochem Sci,2005 2. Glycine transporters: essential regulators of synaptic transmission;Betz;Biochem Soc Trans,2006 3. Glycine transport inhibitors for the treatment of schizophrenia: symptom and disease modification;Javitt;Curr Opin Drug Discov Devel,2009 4. Glutamate-based therapeutic approaches: inhibitors of glycine transport;Lechner;Curr Opin Pharmacol,2006 5. Recent progress in the discovery of non-sarcosine based GlyT1 inhibitors;Wolkenberg;Curr Top Med Chem,2010
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