Investigation of ketone warheads as alternatives to the nitrile for preparation of potent and selective cathepsin K inhibitors-Reference-Cited by-同舟云学术

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Investigation of ketone warheads as alternatives to the nitrile for preparation of potent and selective cathepsin K inhibitors

Published:2009-02 Issue:3 Volume:19 Page:675-679
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Boyd Michael J.,Crane Sheldon N.,Robichaud Joël,Scheigetz John,Black W. Cameron,Chauret Nathalie,Wang Qingping,Massé Frédéric,Oballa Renata M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference30 articles.

1. Human Cathepsin O2, a Matrix Protein-degrading Cysteine Protease Expressed in Osteoclasts

2. Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice

3. Cathepsin K and the Design of Inhibitors of Cathepsin K

4. Cathepsin K inhibitors, 2000 – 2004

5. Design of Cathepsin K Inhibitors for Osteoporosis

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