Identification and hit-to-lead optimization of a novel class of CB1 antagonists-Reference-Cited by-同舟云学术

Identification and hit-to-lead optimization of a novel class of CB1 antagonists

Published:2010-09 Issue:18 Volume:20 Page:5449-5453
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Letourneau Jeffrey J.,Jokiel Patrick,Olson John,Riviello Christopher M.,Ho Koc-Kan,McAleer Lihong,Yang Jingchun,Swanson Robert N.,Baker James,Cowley Phillip,Edwards Darren,Ward Nick,Ohlmeyer Michael H.J.,Webb Maria L.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference16 articles.

1. CB1 Cannabinoid Antagonists: Structure-Activity Relationships and Potential Therapeutic Applications

2. Keynote review: Medicinal chemistry strategies to CB1 cannabinoid receptor antagonists

3. http://www.emea.europa.eu/htms/human/withdraw/withdraw.htm

4. Novel 3,4-diarylpyrazolines as potent cannabinoid CB1 receptor antagonists with lower lipophilicity

5. Synthesis of functionalized 1,8-naphthyridinones and their evaluation as novel, orally active CB1 receptor inverse agonists

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