Discovery and SAR of 4-aminopyrrolidine-2-carboxylic acid correctors of CFTR for the treatment of cystic fibrosis-Reference-Cited by-同舟云学术

Discovery and SAR of 4-aminopyrrolidine-2-carboxylic acid correctors of CFTR for the treatment of cystic fibrosis

Published:2022-09 Issue: Volume:72 Page:128843
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Scanio Marc J.C.,Searle Xenia B.,Liu Bo,Koenig John R.,Altenbach Robert J.,Gfesser Gregory A.,Bogdan Andrew,Greszler Stephen,Zhao Gang,Singh Ashvani,Fan Yihong,Swensen Andrew M.,Vortherms Timothy,Manelli Arlene,Balut Corina,Gao Wenqing,Yong Hong,Schrimpf Michael,Tse Chris,Kym Philip,Wang Xueqing

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference37 articles.

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1. Chaperoning system: Intriguing target to modulate the expression of CFTR in cystic fibrosis;European Journal of Medicinal Chemistry;2024-11

2. Enabling Asymmetric Synthesis of ABBV-3748, a Corrector Compound for the Treatment of Cystic Fibrosis;Organic Letters;2022-09-30