LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs-Reference-Cited by-同舟云学术

LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs

Published:2016-06 Issue:11 Volume:26 Page:2616-2621
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Augustyn Evan,Finke Karissa,Zur Arik A.,Hansen Logan,Heeren Nathan^ORCID,Chien Huan-Chieh,Lin Lawrence,Giacomini Kathleen M.,Colas Claire,Schlessinger Avner,Thomas Allen A.

Funder

University of Nebraska at Kearney (UNK) University Research Fellows (URF) Program

UNK Summer Student Research Program (SSRP)

UNK Research Services Council

Nebraska EPSCoR Undergraduate Research Experiences (URE) Program

National Institutes of Health

Department of Defense

National Institutes of Health’s National Institute of General Medical Sciences

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference46 articles.

1. Large Neutral Amino Acid Transporter Enables Brain Drug Delivery via Prodrugs

2. Targeting the Cerebrovascular Large Neutral Amino Acid Transporter (LAT1) Isoform Using a Novel Disulfide-Based Brain Drug Delivery System

3. Drug delivery via active transport at the blood-brain barrier: affinity of a prodrug of phosphonoformate for the large amino acid transporter

4. Design, Synthesis and Brain Uptake of LAT1-Targeted Amino Acid Prodrugs of Dopamine

5. LAT1-mediated prodrug uptake: a way to breach the blood–brain barrier?

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