1. First paper in this series ‘Pyrazole NNRTIs 1: Design and Initial Optimization of a Novel Template’: Mowbray, C. E.; Burt, C.; Corbau, R.; Perros, M.; Tran, I.; Stupple, P. A.; Webster, R.; Wood A. Bioorg. Med. Chem. Lett. 2009, in press. doi:10.1016/j.bmcl.2009.08.039.
2. The second paper in this series ‘Pyrazole NNRTIs 2: Exploring the Dependency of Potency on Lipophilicity’: Burt, C.; Corbau, R.; Mills, J.; Mowbray, C. E.; Perros, M.; Tran, I.; Price, D.A.; Selby, M. D.; Stupple, P. A.; Webster, R.; Wood, A. Manuscript in preparation.
3. The influence of drug-like concepts on decision-making in medicinal chemistry
4. The same concept was independently proposed by researchers at Pfizer and termed lipE. Ryckmans, T.; Edwards, M. P.; Horne, V. A.; Monica Correia, A.; Owen, D. R.; Thompson, L. R.; Tran, I.; Tutt, M. F.; Young, T. Bioorg. Med. Chem. Lett. 2009, 15, 4406.
5. Corbau, R. G.; Mowbray, C. E.; Perros, M.; Stupple, P. A.; Wood, A. World Patent Application WO 200204424.