Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRγ-Reference-Cited by-同舟云学术

Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRγ

Published:2006-02 Issue:4 Volume:16 Page:821-824
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Chao Esther Y.H.,Collins Jon L.,Gaillard Stéphanie,Miller Aaron B.,Wang Liping,Orband-Miller Lisa A.,Nolte Robert T.,McDonnell Donald P.,Willson Timothy M.,Zuercher William J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference13 articles.

1. To ERR in the estrogen pathway

2. Estrogen receptor-related receptors: orphan receptors desperately seeking a ligand

3. PGC-1 and PERC, coactivators of the estrogen receptor-related receptor γ

4. Peroxisome Proliferator-activated Receptor Coactivator-1α (PGC-1α) Coactivates the Cardiac-enriched Nuclear Receptors Estrogen-related Receptor-α and -γ

5. PPAR coactivator 1 /ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity

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