Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core-Reference-Cited by-同舟云学术

Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core

Published:2015-05 Issue:9 Volume:25 Page:1856-1863
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Sivaprakasam Prasanna,Han Xiaojun,Civiello Rita L.,Jacutin-Porte Swanee,Kish Kevin,Pokross Matt,Lewis Hal A.,Ahmed Nazia,Szapiel Nicolas,Newitt John A.,Baldwin Eric T.,Xiao Hong,Krause Carol M.,Park Hyunsoo,Nophsker Michelle,Lippy Jonathan S.,Burton Catherine R.,Langley David R.,Macor John E.,Dubowchik Gene M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference40 articles.

1. Roles of Glycogen Synthase Kinase 3 in Alzheimer’s Disease

2. GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease

3. Novel players in multiple myeloma pathogenesis: Role of protein kinases CK2 and GSK3

4. GSK-3 and Wnt Signaling in Neurogenesis and Bipolar Disorder

5. Molecular cloning and expression of glycogen synthase kinase-3/factor A.

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