Identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling-Reference-Cited by-同舟云学术

Identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling

Published:2024-01 Issue:1 Volume:14 Page:304-318
ISSN:2211-3835
Container-title:Acta Pharmaceutica Sinica B
language:en
Short-container-title:Acta Pharmaceutica Sinica B

Author:

Rao Yong^ORCID,Su Rui,Wu Chenyan,Chai Xingxing,Li Jinjian,Yang Guanyu,Wu Junjie,Fu Tingting,Jiang Zhongping,Guo Zhikai,Xu Congjun,Huang Ling

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference42 articles.

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5. Lipidomic biomarkers and mechanisms of lipotoxicity in non-alcoholic fatty liver disease;Svegliati-Baroni;Free Radic Biol Med,2019

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3. Marine fungus Aspergillus c1. sp metabolite activates the HSF1/PGC-1α axis, inducing a thermogenic program for treating obesity;Frontiers in Pharmacology;2024-01-25