Ovarian Cancer Risk Variants Are Enriched in Histotype-Specific Enhancers and Disrupt Transcription Factor Binding Sites-Reference-Cited by-同舟云学术

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Ovarian Cancer Risk Variants Are Enriched in Histotype-Specific Enhancers and Disrupt Transcription Factor Binding Sites

Published:2020-10 Issue:4 Volume:107 Page:622-635
ISSN:0002-9297
Container-title:The American Journal of Human Genetics
language:en
Short-container-title:The American Journal of Human Genetics

Author:

Jones Michelle R.,Peng Pei-Chen^ORCID,Coetzee Simon G.,Tyrer Jonathan,Reyes Alberto Luiz P.,Corona Rosario I.,Davis Brian,Chen Stephanie,Dezem Felipe,Seo Ji-Heui,Kar Siddartha,Dareng Eileen,Berman Benjamin P.,Freedman Matthew L.,Plummer Jasmine T.,Lawrenson Kate,Pharoah Paul,Hazelett Dennis J.,Gayther Simon A.

Funder

NIH

Samuel Oschin Comprehensive Cancer Institute Cedars-Sinai Medical Center Developmental Funds

Ovarian Cancer Research Alliance Liz Tilberis Early Career Award

Ovarian Cancer Research Alliance Program

Research Scholar’s Grant from the American Cancer Society

H.L. Snyder Medical Research Foundation

Publisher

Elsevier BV

Subject

Genetics(clinical),Genetics

Reference93 articles.

1. Clinical characteristics and outcomes of BRCA-associated ovarian cancer: genotype and survival;Liu;Cancer Genet.,2012

2. Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer;Bolton;JAMA,2012

3. BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group;Alsop;J. Clin. Oncol.,2012

4. Cells of origin of ovarian cancer: ovarian surface epithelium or fallopian tube?;Klotz;Arch. Gynecol. Obstet.,2017

5. Cell Origins of High-Grade Serous Ovarian Cancer;Kim;Cancers (Basel),2018

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1. Hidden secrets of the cancer genome: unlocking the impact of non-coding mutations in gene regulatory elements;Cellular and Molecular Life Sciences;2024-06-20

2. Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions;The American Journal of Human Genetics;2024-06

3. Human-genome single nucleotide polymorphisms affecting transcription factor binding and their role in pathogenesis;Vavilov Journal of Genetics and Breeding;2023-11-02

4. Functional characterization of human genomic variation linked to polygenic diseases;Trends in Genetics;2023-06

5. In silico enhancer mining reveals SNS-032 and EHMT2 inhibitors as therapeutic candidates in high-grade serous ovarian cancer;British Journal of Cancer;2023-04-29

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