Virtual screening, molecular simulations and bioassays: Discovering novel microsomal prostaglandin E Synthase-1 (mPGES-1) inhibitors

Author:

Babaoglu Zeynep Yagmur,Kilic DeryanurORCID

Funder

Atatürk Üniversitesi

Publisher

Elsevier BV

Subject

Health Informatics,Computer Science Applications

Reference65 articles.

1. Targeting mPGES-1 by a combinatorial approach: identification of the aminobenzothiazole scaffold to suppress PGE2Levels;Chini;ACS Med. Chem. Lett.,2020

2. Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials;Baigent;Lancet,2013

3. Microsomal prostaglandin E synthase-1 promotes lung metastasis via SDF-1/CXCR4-mediated recruitment of CD11b+Gr1+MDSCs from bone marrow;Takahashi;Biomed. Pharmacother.,2020

4. Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells;Hanaka;Proc. Natl. Acad. Sci. U. S. A.,2009

5. Clinical significance of prostaglandin E synthase expression in gastric cancer tissue;Gudis;Hum. Pathol.,2007

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