Integrating pharmacophore mapping, virtual screening, density functional theory, molecular simulation towards the discovery of novel apolipoprotein (apoE ε4) inhibitors-Reference-Cited by-同舟云学术

Integrating pharmacophore mapping, virtual screening, density functional theory, molecular simulation towards the discovery of novel apolipoprotein (apoE ε4) inhibitors

Published:2019-04 Issue: Volume:79 Page:83-90
ISSN:1476-9271
Container-title:Computational Biology and Chemistry
language:en
Short-container-title:Computational Biology and Chemistry

Author:

Johari Surabhi,Sharma Ashwani,Sinha Subrata,Das Aparoop

Publisher

Elsevier BV

Subject

Computational Mathematics,Organic Chemistry,Biochemistry,Structural Biology

Reference30 articles.

1. Memantine added to background cholinesterase-inhibitors reduces agitation and neuropsychiatric symptoms in alzheimer’s disease;Atri;Am. J. Geriatr. Psychiatry,2017

2. Homepage [Internet];Bank R. RCSB PDB,2018

3. Altered levels of amyloid precursor protein intracellular domain-interacting proteins in alzheimer disease;Chakrabarti;Alzheimer Dis. Assoc. Disord.,2014

4. Juliflorine: a potent natural peripheral anionic-site-binding inhibitor of acetylcholinesterase with calcium-channel blocking potential, a leading candidate for Alzheimer’s disease therapy;Choudhary;Biochem. Biophys. Res. Commun.,2005

5. A high-density whole-genome association study reveals that APOE E4 is the major susceptibility gene for sporadic late-onset alzheimer’s disease;Coon;J. Clin. Psychiatry,2007

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. In silico and ADMET molecular analysis targeted to discover novel anti-inflammatory drug candidates as COX-2 inhibitors from specific metabolites of Diospyros batokana (Ebenaceae);Biochemistry and Biophysics Reports;2024-09

2. In silico approach to design new cyclooxygenase-2 (COX-2) inhibitors based on MM/QM and ADMET analysis;Chemical Physics Impact;2024-06

3. Antidiarrhoeal screening of Himalayan edible plant Begonia rubrovenia and its marker followed by its validation using computational analysis;Future Journal of Pharmaceutical Sciences;2024-02-27

4. Screening Techniques for Drug Discovery in Alzheimer’s Disease;ACS Omega;2024-02-05

5. In vitro Evaluation and Molecular Dynamics, DFT Guided Investigation of Antimalarial Activity of Ethnomedicinally used Coptis teeta Wall;Combinatorial Chemistry & High Throughput Screening;2022-02