Virtual screening of p53 mutants reveals Y220S as an additional rescue drug target for PhiKan083 with higher binding characteristics
Author:
Publisher
Elsevier BV
Subject
Computational Mathematics,Organic Chemistry,Biochemistry,Structural Biology
Reference25 articles.
1. Accumulation of wild-type p53 protein upon gamma-irradiation induces a G2 arrest-dependent immunoglobulin kappa light chain gene expression;Aloni-Grinstein;The EMBO Journal,1995
2. Temporal dissection of p53 function in vitro and in vivo;Christophorou;Nature Genetics,2005
3. The pathological response to DNA damage does not contribute to p53-mediated tumour suppression;Christophorou;Nature,2006
4. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas;Xue;Nature,2007
5. In vivo analysis of p53 tumor suppressor function using genetically engineered mouse models;Kenzelmann Broz;Carcinogenesis,2010
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