Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study

Author:

Li Yingying,Peng Jiale,Li Penghua,Du Haibo,Li Yaping,Liu Xingyong,Zhang Li,Wang Liang-Liang,Zuo Zhili

Funder

‘Light of West China’ Program from the Chinese Academy of Sciences

National Natural Science Foundation of China

“The Thousand Talents Program” of Yunnan Province

Strategic Priority Research Program of the Chinese Academy of Sciences

Publisher

Elsevier BV

Subject

Computational Mathematics,Organic Chemistry,Biochemistry,Structural Biology

Reference37 articles.

1. QSAR and docking studies on xanthone derivatives for anticancer activity targeting DNA topoisomerase IIalpha;Alam;Drug Des. Devel. Ther.,2014

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3. Pharmacophore identification and virtual screening for methionyl-tRNA synthetase inhibitors;Bharatham;J. Mol. Graph. Model.,2007

4. The AMP-activated protein kinase cascade--a unifying system for energy control;Carling;Trends Biochem. Sci.,2004

5. AMP-activated protein kinase: nature’s energy sensor;Carling;Nat. Chem. Biol.,2011

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