Diethyldithiocarbamate and disulfiram inhibit MPP+ and dopamine uptake by striatal synaptosomes

Author:

Di Monte Donato,Irwin Ian,Kupsch Andreas,Cooper Stephanie,DeLanney Louis E.,Langston J.William

Publisher

Elsevier BV

Subject

Pharmacology

Reference23 articles.

1. Formation and reduction of glutathione-protein mixed disulfides during oxidative stress;Bellomo;Biochem. Pharmacol.,1987

2. Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase;Chiba;Biochem. Biophys. Res. Commun.,1984

3. Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes;Chiba;Biochem. Biophys. Res. Commun.,1985

4. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by pretreatment with diethyldithiocarbamate;Corsini;European J. Pharmacol.,1985

5. Mechanism of the inhibition of aldehyde dehydrogenase in vivo by disulfiram and diethyldithiocarbamate;Deitrich;Mol. Pharmacol.,1971

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