Role of phosphodiesterase 1 in the pathophysiology of diseases and potential therapeutic opportunities

Author:

Samidurai Arun,Xi Lei,Das Anindita,Iness Audra N.,Vigneshwar Navin G.,Li Pin-Lan,Singla Dinender K.,Muniyan Sakthivel,Batra Surinder K.,Kukreja Rakesh C.

Funder

National Institutes of Health

U.S. Department of Defense

Publisher

Elsevier BV

Subject

Pharmacology (medical),Pharmacology

Reference231 articles.

1. Effects of phosphodiesterase 3,4,5 inhibitors on hepatocyte cAMP levels, glycogenolysis, gluconeogenesis and susceptibility to a mitochondrial toxin;Abdollahi;Molecular and Cellular Biochemistry,2003

2. Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis;Abusnina;Cellular Signalling,2011

3. Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1;Abusnina;Molecular Nutrition & Food Research,2011

4. Agents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle;Afzal;Naunyn-Schmiedeberg’s Archives of Pharmacology,2011

5. Cyclic nucleotide phosphodiesterases (PDEs) in human osteoblastic cells; the effect of PDE inhibition on cAMP accumulation;Ahlstrom;Cellular & Molecular Biology Letters,2005

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