Free light chain kappa and the polyspecific immune response in MS and CIS – Application of the hyperbolic reference range for most reliable data interpretation

Author:

Süße Marie,Reiber Hansotto,Grothe Matthias,Petersmann Astrid,Nauck Matthias,Dressel Alexander,Hannich Malte Johannes

Funder

Siemens Healthineers

The Binding Site

Becton Dickinson, DZHK (German Centre for Cardiovascular Research

Partner Site Greifswald

University Medicine, Greifswald, Germany

DGKL

Publisher

Elsevier BV

Subject

Clinical Neurology,Neurology,Immunology,Immunology and Allergy

Reference31 articles.

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2. Combined use of kappa free light chain index and isoelectrofocusing of cerebro-spinal fluid in diagnosing multiple sclerosis: performances and costs;Crespi;Clin. Lab.,2017

3. K index is a reliable marker of intrathecal synthesis, and an alternative to IgG index in multiple sclerosis diagnostic work-up;Crespi;J. Clin. Med.,2019

4. Determination of kappaFLC and kappa index in cerebrospinal fluid: a valid alternative to assess intrathecal immunoglobulin synthesis;Duranti;J. Neuroimmunol.,2013

5. Revision of the “Guideline of the German Medical Association on Quality Assurance in Medical Laboratory Examinations – Rili-BAEK” (Unauthorized Translation);German medical association,2015

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