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Homocysteine causes vascular endothelial dysfunction by disrupting endoplasmic reticulum redox homeostasis

  • Published:2019-01 Issue: Volume:20 Page:46-59
  • ISSN:2213-2317
  • Container-title:Redox Biology
  • language:en
  • Short-container-title:Redox Biology

Author:

Wu Xun,Zhang Lihui,Miao Yütong,Yang Juan,Wang Xian,Wang Chih-chen,Feng Juan,Wang Lei

Funder

National Key R&D Program of China

National Natural Science Foundation of China

CAS

Publisher

Elsevier BV

Subject

Organic Chemistry,Biochemistry,Clinical Biochemistry

Reference70 articles.

1. Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis;McCully;Am. J. Pathol.,1969

2. Hyperhomocysteinemia: an independent risk factor for vascular disease;Clarke;N. Engl. J. Med.,1991

3. Hyperhomocysteinemia confers an independent increased risk of atherosclerosis in end-stage renal disease and is closely linked to plasma folate and pyridoxine concentrations;Robinson;Circulation,1996

4. Endothelial dysfunction in a murine model of mild hyperhomocyst(e)inemia;Eberhardt;J. Clin. Invest.,2000

5. Homocysteine and oxidative stress;Perna;Amino Acids,2003
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