Cyclometalated Ru(II)-isoquinoline complexes overcome cisplatin resistance of A549/DDP cells by downregulation of Nrf2 via Akt/GSK-3β/Fyn pathway-Reference-Cited by-同舟云学术

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Cyclometalated Ru(II)-isoquinoline complexes overcome cisplatin resistance of A549/DDP cells by downregulation of Nrf2 via Akt/GSK-3β/Fyn pathway

Published:2022-02 Issue: Volume:119 Page:105516
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Chen Lanmei,Wang Jie,Cai Xianhong,Chen Suxiang,Zhang Jingjing,Li Baojun,Chen Weigang,Guo Xinhua,Luo Hui,Chen Jincan

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference78 articles.

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3. L. Xiao, X. Lan, X. Shi, K. Zhao, D. Wang, X. Wang, F. Li, H. Huang, J. Liu, Cytoplasmic RAP1 mediates cisplatin resistance of non-small cell lung cancer, Cell. Death. Dis. 8 (2017) 2803–2803.

4. NRF2 regulates serine biosynthesis in non–small cell lung cancer;DeNicola;Nat. Genet.,2015

5. Regulation and role of nuclear factor-E2-related factor 2 (Nrf2) in multidrug resistance of hepatocellular carcinoma;Tian;Chem. Biol. Interact.,2018

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1. Three Ru(II) complexes modulate the antioxidant transcription factor Nrf2 to overcome cisplatin resistance;Journal of Inorganic Biochemistry;2024-10

2. Insights into the antineoplastic activity and mechanisms of action of coumarin-coordinated 8-hydroxyquinoline ruthenium(II/III) compounds;Journal of Inorganic Biochemistry;2024-10

3. Ru(II)-based complexes containing 2-thiouracil derivatives suppress liver cancer stem cells by targeting NF-κB and Akt/mTOR signaling;Cell Death Discovery;2024-06-03

4. Cyclometalated ruthenium complexes overcome cisplatin resistance through PI3K/mTOR/Nrf2 signaling pathway;Metallomics;2024-01

5. A novel ruthenium complex with 5-fluorouracil suppresses colorectal cancer stem cells by inhibiting Akt/mTOR signaling;Cell Death Discovery;2023-12-16

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